中国农业大学丁杨林课题组近日取得一项新成果。经过不懈努力，他们探明了FERONIA协调质膜纳米团簇对植物耐热性的影响。相关论文于2026年5月21日发表在《科学》杂志上。
在这项工作中，研究人员发现类麦凝集素受体激酶FERONIA （FER）在拟南芥中起着膜锚定热开关的作用。FER组织控制热适应的依赖固醇的纳米纳米。适度的热量通过快速碱化因子34 （RALF34）肽激活FER，并促进其向富含甾醇的纳米结构域募集。在那里，FER成核的动态纳米计富含应力信号成分。这些纳米显微镜稳定了液体有序膜相，激活了热休克转录因子-热休克蛋白信号，增强了耐热性。
然而，在极端高温下，纳米微米迅速分解，防止不良反应。他们的研究结果表明，纳米尺度的膜区隔化是将脂质动力学与植物热恢复力联系起来的关键机制。
据介绍，气候变暖给植物带来了越来越多的热挑战，但质膜生物物理如何促进热适应仍然知之甚少。
附：英文原文
Title: FERONIA orchestrates plasma membrane nanoclusters for plant thermotolerance
Author: Kun Wang, Hanqi Yan, Xin Guo, Qihong Lin, Jing Li, Aoyang Peng, Ying Fu, Zhizhong Gong, Shuhua Yang, Yanglin Ding
Issue&Volume: 2026-05-21
Abstract: Climate warming poses increasing thermal challenges to plants, yet how plasma membrane biophysics contributes to heat adaptation remains poorly understood. In this work, we showed that the malectin-like receptor kinase FERONIA (FER) acts as a membrane-anchored thermal switch in Arabidopsis. FER organizes sterol-dependent nanoclusters that control heat acclimation. Moderate heat activated FER through the RAPID ALKALINIZATION FACTOR 34 (RALF34) peptide and promoted its recruitment to sterol-rich nanodomains. There, FER nucleated dynamic nanoclusters enriched in stress-signaling components. These nanoclusters stabilized liquid-ordered membrane phases and activated heat shock transcription factor–heat shock protein signaling, enhancing thermotolerance. However, under extreme heat the nanoclusters rapidly disassembled, preventing maladaptive responses. Our findings thus establish nanoscale membrane compartmentalization as a key mechanism linking lipid dynamics to plant thermal resilience.
DOI: aeb1752
Source: https://www.science.org/doi/10.1126/science.aeb1752
期刊信息
Science：《科学》，创刊于1880年。隶属于美国科学促进会，最新IF：63.714